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美國VisEn medical  
美國VisEn醫學公司作為分子影像領域的先行者，分子影像領域和技術的開發商，該公司在2005年中期開始銷售其商品化前期的設備和光學探針產品。我們的產品是第一種能夠在動物中真正進行定量、熒光活體三維成像的的光學系統。”，具有專利技術的成像系統和探針 被Massachusetts General Hospital , Harvard Medical School,及其它著名研究機構廣泛采用。

該技術具有定量功能并具有廣泛的應用范圍,應用簡述：腫瘤學、免疫性疾病如關節炎模型等、骨病學、肺病學、心血管病學等。
Pioneering translational in vivo imaging - from research to medicine

With results from genomics and proteomics enhancing our knowledge of the biochemical pathways involved in disease and revealing potential therapeutic targets, there is a growing opportunity to research, understand and measure underlying biological mechanisms and therapeutic responses in vivo.
By developing a unique portfolio of fluorescence-based agents and system solutions that enable scientists to, non-invasively, visualize and quantify biological mechanisms and therapeutic responses deep within the body at the molecular level, VisEn is pioneering a new era of in vivo imaging.
VisEn’s biocompatible fluorescence agents and the company’s breakthrough FMT technology platform for enabling fluorescence-based Quantitative Tomography are already facilitating data generation and translation from profiling to preclinical research and, ultimately, through into clinical trials and medical practice. Today, these powerful imaging solutions are contributing to a deeper understanding of biological mechanisms and therapeutic responses in areas such as inflammatory, cardiovascular, skeletal and pulmonary disease as well as oncology.
Disease
Oncology

Application examples Evaluate disease progression and therapeutic response in tumor models

Study blood vessel density and angiogenesis in tumor models

Assess metastases in tumor models over time

 

Cardiovascular

Application examples Image matrix metalloproteinase (MMP) activity after myocardial infarction

Image proteolytic activity and micro-calcification in models of atherosclerosis

 

Skeletal and Inflammatory

Application examples Evaluate disease progression and therapeutic response in inflammatory disease

Characterize vascular changes and therapeutic response in arthritis models

Characterize bone remodeling in osteoporosis

Measure hormone-induced bone growth and steroid-induced bone resorption

 

Pulmonary

Application examples Visually discriminate, measure and quantify disease severity and therapeutic response in asthma models
 

User-defined in vivo imaging

Application examples Reporting and labeling using agents designed by the user

 

The vision to drive science – translation through to the clinic

While VisEn’s first commercial products are intended for in vivo imaging in disease models of small animals used in research and pre-clinical studies, all developments within the company are focused towards developing translational data, and translational solutions.
Close links with leading research, pharmaceutical and clinical institutions guide all VisEn developments, maintaining a focus towards a future of improved clinical disease understanding and treatment.
Development Partnerships - Expertise for customized solutions

VisEn has a broad range of competencies in developing fluorescence agents and in vivo imaging applications — turning initial concepts into validated products and applications. With a tradition of in vivo technology development and fully functional chemistry, biology and animal imaging capabilities, VisEn can work with partners on specific product and application development programs, tailored to their specific research areas. Contact [email protected] for more information.